Author: damazah@gmail.com

RESEARCH BRIEFINGS 25 June 2026 Cholesterol carried by low-density lipoprotein (LDL) drives heart disease and is cleared by liver cells expressing the receptor LDLR. A cell-signalling mechanism has been discovered through which high cholesterol promotes the enzyme-mediated degradation of LDLR. Blocking this enzyme restores LDLR levels in liver cells, suggesting a new strategy for treating high cholesterol.

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Key events20th over: New Zealand 70-0 (Latham 39, Conway 28) It’d be just like Stokes to finagle a first-over wicket and he’s on the money immediately, Latham edging and scabbing one. But then Conway lasers a drive to the fence at cover. the over ceding six.“Now this is why I love the Guardian OBO!” says Victor Manley. Early doors chat about the structure of words. My favourite phonaesthetic word (don’t pretend like you don’t have one), is ‘bicycle’ which both suggests momentum and a certain clicky machine unreliability. PLUS, as if that weren’t enough, the ‘cyc’ element kinda looks like…

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Indian action star Ajay Devgn is returning to the precinct he knows best. The actor will lead Chauhaan, a feature from director Neeraj Yadav and production houses Jio Studios and Colour Yellow Productions. A theatrical release date of October 1, 2027 has been slated. You can see a first look at Devgn above in a teaser trailer to announce the movie, which the makers say is set in a “gritty and action-packed world.” No further plot details right now, but in the teaser we protestors in Jammu and Kashmir city Pulwama lining up to take on army guards, with Devgn,…

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US Secretary of State Marco Rubio speaks during the 62nd Munich Security Conference (MSC) on February 14, 2026 in Munich, southern Germany. Heads of state and government as well as foreign and defence ministers from all over the world are expected to attend the security policy talks from February 13 to 15, 2026. (Photo by THOMAS KIENZLE / AFP) Top US diplomat Marco Rubio warned on Thursday that a deal with Iran would not come at any price, as he sought to reassure Gulf allies that it would not undermine their security. Rubio was in Bahrain as part of a…

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President William Ruto on Friday said people had a right to protest but warned that anyone “mobilised to destroy property or cause chaos” would not be tolerated.Several political leaders, civil society groups, and human rights organisations have expressed support for peaceful demonstrations, describing them as part of the right to democratic expression protected under the country’s constitution.Ruto’s former deputy Rigathi Gachagua, now a bitter rival, has urged Gen Z activists to stay away from the streets, citing concerns that the protests could turn violent. Instead, he has called on Kenyans to remain at home in a symbolic show of dissent.Last…

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The Federal Government has announced the discovery of what it described as a world-class polymetallic mineral province in Kaduna State containing deposits of platinum group metals, gold, nickel, copper, lithium and rare earth elements. The Minister of Solid Minerals Development, Dele Alake, disclosed this on Wednesday at the opening of the African Natural Resources and Energy Investment Summit (AFNIS) 2026 in Abuja. Mr Alake said the discovery was verified by the Nigerian Geological Survey Agency (NGSA) and represents one of the most significant developments in Nigeria’s mining sector in recent years. According to him, the mineral province was identified through…

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Russian authorities hacked into the phone of a prominent political opponent while he was in custody, using technology made by forensics firm Cellebrite — even after the company had said it cut ties with Putin’s government agencies, according to a new report that raises fresh questions about whether Western tech companies can truly control how their tools are used once they’re in the wild. The case is a cautionary tale for any technology company that sells to governments. Cellebrite, an Israeli outfit with a second headquarters in Virginia that sells to governments all over the world — including in the…

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The price of Brent crude has reached its lowest since February 27, before the war started.Published On 25 Jun 202625 Jun 2026Oil prices have extended their decline to levels last seen before the start of the Iran war, as expectations of rising supply from the Middle East outweighed demand concerns.Prompt-month Brent crude futures for August delivery fell $1.06 (1.44 percent) to $72.68 a barrel by 06:39 GMT, while US West Texas Intermediate (WTI) lost 76 cents (1.08 percent) to $69.58 a barrel.Recommended Stories list of 4 itemsend of listBoth contracts hit their lowest since February 27.August Brent was trading lower…

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Several people, including a site engineer and a contractor, are reportedly trapped under the rubble of a collapsed five-storey building in Port Harcourt, Rivers State. The building was under construction when it caved in on Wednesday. Emergency responders have been trying to rescue survivors. The building collapsed along Peter Odili Road, Trans-Amadi, Port Harcourt, at about 9 a.m., according to witnesses, triggering panic among residents and workers in the area. As of Wednesday night, three persons had been rescued alive from the debris, according to reports by News Central TV. Rescuers were still searching for other victims believed to be…

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